In the development of skincare products, the core requirements for raw materials are clear bioactivity, controllable safety, and market differentiation.
BIO-FRGE PLUS (Red Ginseng Ferment Filtrate) is based on a traditional Korean botanical, enhanced by modern precision fermentation technology. With a clear mechanism of action targeting anti-wrinkle and anti-aging pathways, it provides a viable, high-efficacy solution for skin concerns such as fine lines and dullness.

INCI: Water, Glycerin, Caprylyl Glycol, 1,2-Hexanediol, Lactobacillus/Panax Ginseng Root Ferment Filtrate
1. The Fusion of Red Ginseng and Fermentation

1. Korean Red Ginseng: The Foundation of Activity
The raw material uses Korean Red Ginseng derived from fresh Panax ginseng C.A. Meyer (including the peel). After steaming and drying, it takes on a light yellow-brown to reddish-brown hue and has a shelf life exceeding 10 years. Its core value lies in Ginsenosides (saponins)—and the root of Korean Red Ginseng is globally recognized for its outstanding saponin content.
2. Precision Fermentation Technology
Utilizing advanced precision fermentation, specific enzymes break down the nutritional components of Red Ginseng. This process reduces the inherent bitterness of the ginseng while significantly boosting the concentration of key active ingredients:
- Ginsenoside Rg3 (Anti-wrinkle): 5 times higher than ordinary Red Ginseng.
- Ginsenoside Rk1: 9 times higher than ordinary Red Ginseng.


2. Key Efficacy Mechanisms
1. Anti-Aging: Regulating Aging Factors
Skin aging is closely linked to DNA damage, the accumulation of Reactive Oxygen Species (ROS), and inflammation.
BIO-FRGE PLUS activates SIRT1 and SIRT3 (known as “Longevity Genes” and core regulators of aging):

- SIRT1 & SIRT3 Activation: Helps repair DNA in the cell nucleus.
- Mitochondrial Protection: Once activated, SIRT3 helps inhibit the production of free radicals like ROS in the mitochondria.


2. Anti-Pollution
Tests indicate that BIO-FRGE PLUS inhibits the mRNA expression of the aryl hydrocarbon receptor (AhR) and CYP1A1. This mechanism reduces the adverse effects of environmental pollutants on the skin.


3. Anti-Glycation
BIO-FRGE PLUS inhibits the mRNA expression of the Receptor for Advanced Glycation End-products (RAGE). This reduces the binding of AGEs (Advanced Glycation End-products) to collagen, thereby mitigating the skin-aging effects of glycation (sugar-induced aging).

4. Optimizing Skin Rhythm (Circadian Balance)
Disrupted sleep schedules can break the balance of the skin’s circadian rhythm. BIO-FRGE PLUS promotes the expression of the Bmal-1 gene (a key regulator of skin rhythm), helping the skin restore its normal biological clock and repair cycles.


3. Formulation Applications
Beyond acting as a high-performance active ingredient, BIO-FRGE PLUS possesses a natural deep brown hue, allowing it to serve as a “functional natural colorant” (a pigment that isn’t just a pigment).
Formula Spotlight: Pure Anti-Wrinkle Eye Cream

Formula Code: SL240602
Texture: Satin-soft, melting upon contact.
- Uses SIMULGEL EG as the primary thickener for a “melt-on-skin” sensation.
- Emulsified with SENSANOV WR & MONTANOV 82 to hold nearly 30% oil, creating a semi-translucent, luxurious balm. It absorbs quickly, leaving a moisturizing film that softens lines.
Efficacy: Firming, Brightening, and Smoothing
- BIO-FRGE PLUS: Promotes the expression of longevity proteins (Sirt 1 & Sirt 3), optimizes skin rhythm, and lends the cream a natural light brown color.
- Plant-Derived RICE PDRN: Brightens the eye area.
- Pro-Xylane (Hydroxypropyl Tetrahydropyrantriol): Stimulates collagen production to plump the under-eye area.
- PROLISTIN: Captures free copper ions to smooth wrinkles and rejuvenate the eye contour.
Summary:
BIO-FRGE PLUS Red Ginseng Ferment Filtrate takes a core traditional Korean ingredient and optimizes it through modern fermentation technology. With clear in vitro data supporting its anti-aging, anti-pollution, and anti-glycation benefits, it meets strict safety and compliance standards. For brands seeking to develop multidimensional skincare with a strong cultural narrative, this is an active ingredient worth watching!

